Chronic lymphocytic thyroiditis

on 28.8.08 with 0 comments

  • chronic autoimmune thyroiditis (Hashimoto disease) is T-cell mediated autoimmunity causing thyroid destruction

  • sometimes, Graves and Hashimoto disease can occur together, and this is termed hashitoxicosis

    • Graves is antibody-mediated disease

    • Hashimoto is T-cell-mediated disease

  • Hashimoto disease can occur in polyglandular autoimmune syndrome type 2

    • with this, patients also have hypothyroidism, adrenal insufficiency, diabetes mellitus type I

  • Hashimoto encephalopathy: autommunity to CNS proteins: confusion, seizure, coma. brain biopsies are performed in this setting

Category: Pathology Notes



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