ECM interactions and growth factors influence wound healing

on 27.8.08 with 0 comments

  • there are a variety of growth factors involved

  • integrins and laminins attach cells to the extracellular matrix

  • a lot of the invasion, metastasis, and vessel growth associated with malignancy is really just a perversion of this entire process; Darwinian selection for cancer cells leads to cancer cells hijacking these same signaling pathways to carry out invasion and metastasis

  • you can stop certain cancer cells from invading by taking away these signals

Category: Pathology Notes



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