on 30.1.09 with 0 comments

  • Meningovascular

    • Most common form

    • See plasma cells in the meninges

    • Special stains will show spirochetes

  • Parenchymal (gummas) – more of a granulomatous reaction

  • General paresis

    • Spirochetes invade the brain (and can be seen with special stains) and cause gliosis and other reactive changes

    • Fe deposits are common and there is a progressive neuronal loss

  • Tabes dorsalis

    • Looks similar to vacuolar myelopathy of AIDS

    • Involves posterior columns of the spinal cord

    • Will not see spirochetes with special stain

    • Present with sensory disturbances, shooting pains, loss of proprioception and ataxia

Category: Pathology Notes



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