Chemical injuries resulting in hemolysis

on 4.3.09 with 0 comments

  • Lead poisoning

    • Lead interferes with aminolevulinic acid dehydratase and ferroketolase, which are involved in incorporating iron into the heme molecule

    • Instead, the iron is put into zinc-protoporphyrin or free erythrocyte protoporphyrin, both of which are increased

    • There is a microcytic, hypochromic, hemolytic anemia with coarse basophilic stippling of the erythrocytes

  • Other chemicals like sulfas, pyridium, furadantin, salicylates, mothballs, arsine, copper, etc

Category: Medical Subject Notes , Pathology Notes



Post a Comment