Dental considerations in the Diabetic

on 6.12.05 with 0 comments


Corticosteroids may increase glucose levels. High doses of salicylate analgesics (aspirin et al.) and certain NSAIDs (especially Ibuprofen and Naproxen) increase hypoglycemic action.

Type 1 diabetics are at risk for leukopenia, thrombocytopenia, delayed wound healing,

  • increased risk of infection, hypo-hyperglycemic episodes, angioapathy, neuropathy, retinopathy, platelet hyperaggregability, periodontal disease, and gingival bleeding. Beta-blockers may mask sings of hypoglycemia. Alcohol enhances insulin action.

Oral antidiabetic agents (OAAs)

In Type 2 diabetics: glucocorticoids may increase glucose, beta-blockers may inhibit

  • insulin release, salicylates and some NSAIDs cause serum protein displacement of OAA’s, leading to hypoglycemia, antabuse type reaction with alcohol, metformin and pheformin cause elevated lactoate (lactic acidosis), sulfur-containing OAA’s, weight loss reduces OAA dose needs, and hyperinsulinemia may be present.

Category: Pharmacology Notes



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